For patients with pulmonary arterial hypertension (PAH) WHO Class III or IV

		A FREE support and education program for patients on Tracleer® (bosentan). Take the first step on your pathway of support... For more information about PAH and your medication, visit www.Tracleer.com.	PAH is a complex, often misunderstood disease. Sure StepsTM can give you reasons for hope. When you enroll, you'll receive one-to-one attention from a Nurse Counselor who will be available by phone to answer your questions. You'll also get:  Ongoing informational newsletters  Important tips about coping with    PAH  Tools to help you enjoy life's    everyday pleasures

IMPORTANT INFORMATION ABOUT TRACLEER

Liver Damage Tracleer can cause serious liver damage, including in rare cases liver failure and, in situations with regular liver testing, unexplained liver cirrhosis. So you must have a blood test to check your liver function before you start Tracleer and each month after that. Tell your doctor if you believe you have liver problems.

Major Birth Defects Tracleer is very likely to cause major birth defects. It is important not to be or to become pregnant while taking Tracleer and to have a pregnancy test before you start the drug and each month thereafter. Because hormonal contraceptives may not be effective when you are taking Tracleer, it is also very important for you to use two different kinds of birth control while taking Tracleer. Because of these risks, Tracleer may only be prescribed by your doctor through the Tracleer Access Program.

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